social isolation¶

Type: Entity
Confidence: ★★★★★ Established

Evidence Graph¶

Summary¶

Social isolation inhibits oxytocin neuron activity, disrupting the VTA dopamine pathway. Lack of social connection increases all-cause mortality by ~50% (meta-analysis of 148 studies, 300k+ participants).

Timeline¶

Added to Knowledge Graph: 2026-02-04 13:27 UTC
Valid Since: 2026-02-04

Relationships¶

Supports¶

• INHIBITS: oxytocin neuron activity
  Social isolation inhibits oxytocin neuron activity 📅 Valid since: 2026-02-04 📚 Mentioned in 1 episode(s)

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Last updated: 2026-02-04